CellulaBright Pro Serum

Professional-Grade Targeted Correction for Melasma and Hyperpigmentation.

0.3% 4-Butylresorcinol, 4% Niacinamide, 3% Tranexamic, 5% Azelaic Acid, 5% Ascorbyl Glucoside

CellulaBright Pro Serum is a concentrated, multi-mechanism corrective treatment engineered to disrupt the appearance of stubborn melasma, post-inflammatory hyperpigmentation (PIH), and sun spots.This advanced depigmenting serum is formulated to address hyperpigmentation at its biological source, while preserving and strengthening the skin barrier. It combines clinically proven melanin inhibitors with anti-inflammatory, antioxidant, and barrier-supportive ingredients to deliver visible brightening with high tolerability.

INGREDIENTS

Aqua, Propylene Glycol, Ascorbyl Glucoside, Azelaic Acid, Niacinamide, Glycerin, Tranexamic Acid, Butylene Glycol, Panthenol, Sodium Hydroxide, 1,2-Hexanediol, Hydroxyacetophenone, Hydroxyethylcellulose, Allantoin, Sodium Hyaluronate, Magnesium Ascorbyl Phosphate, 3-O-Ethyl Ascorbic Acid, Ascorbyl Peptide, Sodium Ascorbyl Phosphate, Disodium EDTA, Caprylic/Capric Triglyceride, 4-Butylresorcinol, Ergothioneine, Lecithin, Camellia Sinensis Leaf Extract, Ethylhexylglycerin, Tetrahexyldecyl Ascorbate, Tocopheryl Acetate

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How It Works on Melasma & PIH

Hyperpigmentation such as melasma and PIH is driven by overactive melanocytes, inflammation, oxidative stress, and impaired barrier function. This formula targets all major pathways involved in pigment formation and persistence.

Professional-Grade, Derm-Developed.

Stubborn hyperpigmentation and melasma require a sophisticated, multi-targeted approach. This potent, yet refined, serum is the culmination of advanced dermatological science, formulated to deliver professional-level results in the fight against discoloration.

Key Active Technologies & Their Benefits

4-Butylresorcinol (0.3%) — Core Melanin Inhibitor

A highly potent tyrosinase inhibitor, 4-Butylresorcinol directly suppresses melanin synthesis at the enzymatic level. It is recognized as one of the most effective non-hydroquinone ingredients for melasma, outperforming traditional brightening agents such as kojic acid and arbutin.
Benefit: Visibly reduces dark patches and uneven skin tone with good skin tolerance.

Azelaic Acid (5%) — Pigment Regulation & Anti-Inflammatory Action

Azelaic acid helps normalize melanocyte activity while calming inflammation that often worsens melasma and PIH. It also helps prevent new pigmentation triggered by acne or irritation.
Benefit: Treats existing pigmentation while reducing the risk of rebound or post-inflammatory darkening.

Tranexamic Acid (3%) — Melasma-Specific Support

Tranexamic acid targets UV- and inflammation-induced melanocyte activation, making it particularly effective for hormonally influenced or vascular-associated melasma.
Benefit: Improves stubborn pigmentation and enhances the effectiveness of other melanin inhibitors.

Niacinamide (4%) — Melanosome Transfer Inhibition & Barrier Repair

Niacinamide does not only brighten—it reduces the transfer of melanin from melanocytes to surrounding skin cells while strengthening the skin barrier.
Benefit: More even skin tone, improved resilience, and reduced sensitivity during active treatment.

Ascorbyl Glucoside (5%) — Antioxidant Brightening Support

This stable vitamin C derivative provides antioxidant protection against UV-induced oxidative stress, a key trigger for melasma recurrence. It also contributes to overall skin luminosity.
Benefit: Enhances radiance and supports long-term pigment control with excellent stability.

Soothing & Barrier-Supporting Complex

• Panthenol (1%) – strengthens the barrier and improves tolerance
• Allantoin (0.2%) – calms irritation and supports skin recovery
• Sodium Hyaluronate (0.2%) – hydrates and improves skin elasticity
• Green Tea Extract (0.3%) – antioxidant and anti-inflammatory support

Benefit: Reduces irritation-induced pigmentation and allows consistent, long-term use—essential in melasma treatment.

Why This Formula Stands Out

• ✔ Multi-pathway melanin inhibition (synthesis + transfer + inflammation)
• ✔ High-efficacy actives at evidence-based concentrations
• ✔ Designed for melasma-prone and PIH-prone skin
• ✔ Balanced with barrier-protective and soothing ingredients
• ✔ Suitable for long-term use when combined with sun protection

This formulation delivers strong depigmenting performance without compromising skin health, which is critical for chronic conditions such as melasma.

Directions for Use

Frequency:

• Once daily (evening) for sensitive skin or first-time users
• Twice daily (morning & evening) if skin tolerates well

How to Apply:

• Cleanse the skin gently and pat dry.
• Apply a thin, even layer to areas affected by melasma or PIH.
• Allow to fully absorb before applying moisturizer.

Daytime Use:

• Always follow with a broad-spectrum sunscreen SPF 50+ in the morning.
• Sun protection is essential to prevent recurrence and maximize results.

Important Use Guidelines

• Avoid combining with strong exfoliating acids or retinoids during the first 2–3 weeks unless advised by a professional.
• Mild tingling may occur initially due to active ingredients; this usually subsides as the skin adapts.
• Consistent use and strict photoprotection are essential for optimal results.

Expected Results

• PIH: visible improvement in 4–6 weeks
• Melasma: progressive lightening over 8–12 weeks
• Skin tone: improved uniformity and clarity with continued use

Warnings & Precautions

• For external use only.
• Avoid contact with eyes, eyelids, and mucous membranes.
• Do not apply on broken, irritated, or compromised skin.
• A mild tingling sensation may occur during initial use due to active ingredients; this is generally temporary.
• If persistent irritation, burning, or redness occurs, discontinue use and consult a healthcare professional.
• Not recommended for use immediately after aggressive aesthetic procedures (e.g., deep chemical peels, ablative lasers) unless advised by a professional.

 

Contraindications

• Known hypersensitivity to any of the listed ingredients.
• Use with caution on highly reactive or sensitized skin.
• Not recommended during pregnancy or breastfeeding unless approved by a physician, due to the presence of strong depigmenting actives.

Sun Exposure Warning

• This product contains ingredients that increase photosensitivity.
• Daily use of a broad-spectrum sunscreen SPF 50+ is mandatory during treatment and for at least 2 weeks after discontinuation.
• Excessive sun exposure without protection may reduce treatment effectiveness and increase the risk of pigmentation recurrence.

Storage

• Store in a cool, dry place away from direct sunlight.
• Keep container tightly closed.
• Keep out of reach of children.

Professional Melasma & PIH Treatment Protocol

(For clinic use or advanced home-care guidance)

Indications

• Epidermal and mixed melasma
• Post-inflammatory hyperpigmentation (PIH)
• Uneven skin tone caused by inflammation, acne, or UV exposure

Home-Care Protocol (Standard)

Morning Routine

• Gentle, non-foaming cleanser
• Melanin Inhibitor Serum (thin layer on affected areas)
• Barrier-supporting moisturizer (if needed)
• Broad-spectrum sunscreen SPF 50+ (mandatory)

Evening Routine

• Gentle cleanser
• Melanin Inhibitor Serum
• Moisturizer suited for sensitive or pigment-prone skin

Introduction Schedule (Recommended)

To minimize irritation and rebound pigmentation:

• Week 1–2: Apply once daily (evening only)
• Week 3 onward: Increase to twice daily if well tolerated

Professional Combination Protocols

With Chemical Peels (Non-Ablative)

• Discontinue product 3–5 days before superficial peels
• Resume 5–7 days after skin normalization
• Helps prevent post-procedure PIH

With Retinoids

• Alternate nights initially (retinoid one night, serum the next)
• Avoid simultaneous application in early phases

With Laser / Energy Devices

• Use as pre-treatment conditioning for 2–4 weeks
• Resume post-procedure once barrier integrity is restored

Expected Clinical Timeline

• 4–6 weeks: Improvement in PIH and skin brightness
• 8–12 weeks: Visible lightening of melasma patches
• Long-term: Improved tone uniformity with strict SPF adherence

Professional Notes

• Melasma is a chronic, relapsing condition — maintenance therapy and sun protection are essential.
• Consistency and tolerance are more important than aggressive application.
• This serum is designed for long-term pigment control, not short-term bleaching.

DermaCalmRx

POST ACNE RECOVERY SERUM

ERYTHEMA ERASE: THE FIRST SERUM DESIGNED TO FADE POST-ACNE REDNESS.

PIE Recovery & Calming Serum.
Stop waiting for red marks to fade on their own. Our targeted formula calms inflammation, strengthens capillaries, and supports skin's natural healing process to visibly reduce the appearance of PIE (Post-Inflammatory Erythema).

Red Marks Aren't Scars. They're a Call for Calm.

Those stubborn red, pink, or purple spots left behind after a pimple heals are not scars—they are PIE. They are actually dilated, inflamed capillaries trapped under the skin’s surface. Traditional "brightening" serums often fail because PIE isn't a pigment problem. Erythema Erase is the targeted solution, addressing the root cause: vascular inflammation.

Key Benefits:

• Visibly Reduces Redness: Calms inflamed capillaries to fade the appearance of existing red marks.
• Strengthens Skin Resilience: Reinforces the skin's barrier to prevent new PIE from forming.
• Soothes & Repairs: Delivers immediate soothing relief to angry, sensitized skin.
• Non-Irritating & Restorative: Works in harmony with your skin's natural healing process.

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The Science of Soothing: Why This Serum Works Where Others Fail

Advanced AHA + BHA Exfoliating Solution

Clarifying, resurfacing, and tone-refining treatment

10% Glycolic Acid • 2% Salicylic Acid • 0.3% Allantoin

This advanced exfoliating solution combines glycolic acid (AHA) and salicylic acid (BHA) at clinically effective concentrations to promote controlled skin renewal, improve texture, and support the treatment of acne, PIH, and uneven skin tone. The formula is balanced with soothing and barrier-supporting ingredients to maximize efficacy while minimizing irritation.

How This Formula Works on the Skin

Uneven texture, clogged pores, acne, and post-inflammatory pigmentation are often caused by excessive corneocyte buildup, impaired desquamation, and inflammation. This formula targets these issues through dual-action chemical exfoliation, while maintaining skin comfort.

Key Active Ingredients & Their Skin Benefits

Glycolic Acid (10%) — Surface Resurfacing & Brightening

Glycolic acid is a low–molecular weight alpha hydroxy acid that penetrates efficiently into the stratum corneum. At 10%, it promotes exfoliation of dead skin cells, accelerates cell turnover, and improves skin smoothness and radiance.
Benefit: Refines skin texture, enhances luminosity, and helps fade superficial hyperpigmentation over time.

Salicylic Acid (2%) — Pore Cleansing & Anti-Inflammatory Action

Salicylic acid is a beta hydroxy acid with oil-soluble properties, allowing it to penetrate into pores and dissolve excess sebum and debris. It also has anti-inflammatory and antibacterial effects.
Benefit:Clears congested pores, reduces acne lesions, and helps prevent PIH following breakouts.

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Dual AHA + BHA Technology

The combination of glycolic acid and salicylic acid allows for multi-level exfoliation:

• AHA works on the skin surface to smooth texture and improve tone
• BHA works inside pores to reduce congestion and inflammation

Benefit: More comprehensive exfoliation than single-acid products, leading to clearer, smoother, and more even-looking skin.

Soothing & Barrier-Support Complex

• Panthenol – Supports barrier repair and reduces irritation
• Allantoin – Calms skin and promotes recovery
• Caprylyl Glycol – Hydration and antimicrobial support

Benefit: Helps counteract dryness and sensitivity commonly associated with chemical exfoliation.

Formulation Stabilizers & Skin Comfort Enhancers

• Propanediol & Propylene Glycol – Improve penetration and hydration
• PEG-40 Hydrogenated Castor Oil & Trideceth-9 – Solubilization and sensory balance
• Xanthan Gum – Controlled viscosity and even application
• Benzophenone-4 – Protects formula integrity from UV degradation
• Disodium EDTA – Enhances stability and preservation

Why This Product Stands Out

• ✔ Clinically relevant concentrations of AHA (10%) and BHA (2%)
• ✔ Dual-action exfoliation for surface renewal and pore purification
• ✔ Supports acne-prone and PIH-prone skin
• ✔ Balanced with soothing ingredients to improve tolerability
• ✔ Suitable for progressive, controlled exfoliation programs

This formulation offers professional-level exfoliation while remaining suitable for structured home care when used correctly.

Directions for Use

Frequency:

• 1–2 times per week for sensitive or first-time users
• Up to 2–3 times per week for tolerant skin

How to Apply:

• 1. Cleanse skin thoroughly and pat dry.
• 2. Apply a thin, even layer to the face, avoiding the eye and lip area.
• 3. Leave on the skin (do not rinse) unless otherwise instructed by a professional.
• 4. Follow with a soothing moisturizer.

Important Use Guidelines

• 1. This product contains high-strength exfoliating acids.
• 2. Mild tingling or stinging may occur on application; this is normal.
• 3. If persistent burning or irritation occurs, discontinue use.
• 4. Do not use on broken, irritated, or compromised skin.

Sun Protection Warning

• Chemical exfoliation increases skin sensitivity to UV radiation.
• Daily use of broad-spectrum sunscreen SPF 50+ is mandatory during use and for at least 7 days after application.
• Avoid excessive sun exposure.

Expected Results

• After 1–2 weeks: smoother skin texture and clearer pores
• After 3–4 weeks: reduction in acne congestion and superficial PIH
• With continued use: brighter, more even skin tone

Professional Notes

• Not recommended for daily use.
• Avoid combining with retinoids or other exfoliating acids on the same day.
• Ideal as a pre-treatment step before brightening or melasma-focused therapies.

How It Supports Melasma & PIH-Prone Skin

While melasma itself requires melanin inhibitors, controlled exfoliation is a critical supportive step in pigmentation management. This formula:

• 1. Removes excess corneocyte buildup that traps pigment
• 2. Enhances penetration and efficacy of melanin-inhibiting treatments
• 3. Reduces acne and inflammation that can trigger PIH
• 4. Improves skin texture and luminosity

Used correctly, it helps maintain clearer skin and prevent new pigmentation, especially when paired with depigmenting serums and daily sun protection.

 

Professional Treatment Integration

With Melasma or PIH Serums

• 1. Use exfoliant at night only
• 2. Apply depigmenting serums on non-exfoliation days initially
• 3. Improves penetration and treatment response

With Retinoids

• 1. Do not use on the same night
• 2. Alternate evenings to minimize irritation

Pre-Procedure Conditioning

• 1. Can be used for 2–3 weeks prior to superficial peels or laser (under professional guidance)

Expected Results Timeline

• 1–2 weeks: smoother texture, clearer pores
• 3–4 weeks: reduced congestion and fewer inflammatory lesions

Ongoing use: improved skin clarity and reduced PIH risk

Warnings, Contraindications & Safety Information

Warnings & Precautions

Application Method

• Cleanse skin thoroughly and dry completely
• Apply a thin, even layer to the face, avoiding eyes and lips
• Leave on the skin (do not rinse) unless otherwise directed
• Follow with a soothing, barrier-supporting moisturizer
• For external use only
• Avoid contact with eyes, lips, and mucous membranes
• Do not apply to broken, irritated, or compromised skin
• Tingling or mild stinging may occur upon application; this is normal
• Discontinue use if persistent irritation, burning, or redness develops

Contraindications

• Hypersensitivity to salicylic acid, glycolic acid, or any formulation components
• Not recommended for individuals with aspirin sensitivity
• Not suitable for use during pregnancy or breastfeeding unless advised by a healthcare professional

Sun Sensitivity Warning

• This product increases skin sensitivity to UV radiation
• Daily use of broad-spectrum sunscreen SPF 50+ is mandatory during use and for at least 7 days after application
• Avoid excessive sun exposure

Storage

• Store below 25°C, away from direct sunlight
• Keep container tightly closed
• Keep out of reach of children

Professional Use Protocol & Directions of Use (Home-Care Directions)

Frequency

• Beginner / Sensitive Skin: 1× per week
• Normal to Oily Skin: 2× per week
• Experienced / Acne-Prone Skin: up to 2–3× per week

Not intended for daily use.

Final Professional Note

This formulation provides strong, controlled exfoliation suitable for structured treatment plans. When used responsibly and paired with sun protection and barrier care, it is a valuable support product in acne, PIH, and melasma management programs.